Masha Sibinovic

Pharmaceutical competitive intelligence and life sciences research professional with more than six years of experience supporting international clients across oncology, diagnostics, precision medicine, cardiovascular disease, and other therapeutic areas. Experienced in deep-dive secondary research, competitive landscape assessment, scientific conference coverage, news monitoring, and the development and continuous updating of clear, evidence-based intelligence reports. Skilled at […]

Troubleshooting Inconsistent Engraftment in a Murine Leukemia Model

Our team is running a disseminated AML xenograft model (luciferase-tagged cell line, NSG mice, IV injection) to support lead compound efficacy studies. Over the last three cohorts, engraftment has been inconsistent: bioluminescence signal is present but highly variable between animals within the same cohort & roughly 30% of animals show no detectable engraftment by day […]